Abstract:
Alzheimer’s disease (AD) is a neurodegenerative condition that mainly affects the
elderly, leading to progressive deterioration of cognitive functions. This study aimed to
investigate the efficacy of vitamin B12 in the prevention and treatment of AD,
considering the crucial role of this vitamin in the health of the nervous system. Vitamin
B12 deficiency is common in the elderly, due to the decrease in absorption capacity
with age, and is associated with the accumulation of homocysteine, a risk factor for
neurodegenerative diseases. The methodology was based on an integrative literature
review, with analysis of scientific studies published in the last ten years. The results
indicated that adequate levels of vitamin B12 can reduce the risk of cognitive decline,improve neurological function and reverse initial data in AD. It is concluded that B12
supplementation in the elderly is beneficial, highlighting the importance of adequate
nutrition and monitoring of levels of this vitamin in populations at risk.
