FERREIRA, Gabryella Romany; BOAS, João Victor Neto Vilas; ALBUQUERQUE, Luis Fernando Duarte
Abstract:
Antimicrobial resistance stands out as one of the greatest challenges to public, animal,
and environmental health, especially due to the intensive use of drugs in poultryproduction. Among the most commonly used antimicrobials is sulfamycin, a member of
the sulfonamide group, widely employed in the treatment and prevention of bacterial
infections in birds. The continuous and often indiscriminate use of this drug has favored
the emergence and spread of resistant bacterial strains, compromising therapeutic
efficacy and posing risks to food safety and sustainable production. This study,
developed as a literature review, aimed to gather and analyze scientific information
regarding the use of sulfamycin in poultry and its relationship with the development of
antimicrobial resistance. National and international databases were consulted,
including articles, dissertations, and official documents addressing resistance
mechanisms, the main microorganisms involved, and the impacts under the One
Health approach. The results indicate that resistance to sulfamycin arises from genetic
mutations, gene transfer, and inadequate management practices, leading to sanitary,
economic, and environmental losses. Therefore, it is evident that integrated control
strategies are required, based on the rational use of antimicrobials, biosafety
measures, and the adoption of alternative therapies such as probiotics, herbal
medicines, and vaccines. It is concluded that combating antimicrobial resistance
demands coordinated efforts among public, productive, and scientific sectors, aiming
for a more sustainable poultry industry aligned with the One Health concept.
