SANTOS, Isadora Ribeiro dos; RODRIGUES, Kaynanellyffer Thyenyffer Lopes Ribeiro de Deus; COSTA, Thalyssa Myrelle Pereira de Morais; ALBUQUERQUE, Luis Fernando Duarte
Abstract:
Antimicrobial resistance represents one of the greatest and most current challenges in
veterinary medicine, especially in the management of skin diseases in dogs. These
skin conditions, often associated with opportunistic pathogens such as Staphylococcus
pseudintermedius, Staphylococcus aureus, and Pseudomonas aeruginosa, have
shown increasing rates of resistance, complicating treatment and favoring relapses.
The objective of this study was to analyze, through an integrative literature review, the
resistant and multidrug-resistant agents present in canine skin diseases, as well as the
antimicrobials involved in resistance and the main recommendations for controlling this
process. The methodology consisted of a bibliographic survey of national and
international databases, considering recent publications addressing antimicrobial
resistance in dogs with skin conditions. The results showed a significant prevalence of
multidrug-resistant microorganisms, particularly Staphylococcus pseudintermedius
and Pseudomonas aeruginosa, with high rates of resistance to ampicillin, amoxicillin
plus clavulanate, clindamycin, enrofloxacin, and amoxicillin plus clavulanate, and
trimethoprim plus sulfamethoxazole, respectively. This reinforces the importance of
prescribing antimicrobials, always in conjunction with microbiological diagnosis,
establishing therapeutic protocols based on updated local data on resistance, and
communicating with the owner, reinforcing the importance of treatment adherence.
Therefore, antimicrobial resistance in canine skin diseases is a challenge that requires
integrated actions among veterinarians, researchers, regulatory agencies, and owners
for an effective approach, appropriate clinical management, and potentially reducing
the spread of resistant strains.