FATORES QUE INFLUENCIAM A PREDISPOSIÇÃO GENÉTICA E HEREDITÁRIA DA EPILEPSIA IDIOPÁTICA EM CÃES

Abstract

Idiopathic epilepsy is a common neurological disorder in dogs, characterized by recurrent epileptic seizures with no apparent structural or metabolic cause. Genetic factors play a central role in predisposition to the disease, especially in purebred dogs. The objective was to investigate the factors that influence the genetic and hereditary predisposition to idiopathic epilepsy in dogs, considering how these mutations impact affected animals and how specific genetic factors can elucidate the mechanisms underlying predisposition to the disorder. The methodology used was exclusively a literature review. The results showed that although the etiology of idiopathic epilepsy in dogs remains elusive, scientific evidence suggests that its predisposition results from a multifactorial interaction between genetic, environmental, and physiologicalcomponents, the clinical expression of which may vary individually among affected animals.