BORGES, Andreyna dos Santos; DORNELES, Williana Maria; OLIVEIRA JUNIOR, Edilson Ribeiro
Abstract:
Cardiovascular diseases are among the leading causes of maternal morbidity and
mortality, representing a significant challenge during pregnancy and the postpartum
period due to the physiological changes inherent to gestation and the need forspecific pharmacological therapies. The use of medications in this context requires
strict attention, as several drugs cross the placental barrier or are excreted in breast
milk, potentially posing risks to the fetus and newborn. In this regard, the present
study aimed to evaluate the risks and benefits of cardiovascular drug use in pregnant
and postpartum women, as well as to discuss safe and rational management
strategies for treating these conditions. This is an integrative literature review,
considering publications available in Portuguese and English. The results showed
that the safe management of cardiovascular drugs in pregnant and postpartum
women depends on a careful assessment of risks and benefits, taking into account
the physiological changes of the gestational and puerperal period. The
multidisciplinary approach, especially the role of the clinical pharmacist, is essential
to ensure treatment efficacy and maternal-fetal safety. It is concluded that the careful
selection of therapies, combined with evidence-based protocols, contributes to
humanized and effective care, minimizing risks to the fetus and newborn and
promoting better clinical outcomes.
