Abstract:
This work presents an integrative review on the clinical application of plaque-rich fibrin
(PRF) in minor oral surgery, focusing on the effects of PRF on bone healing and
prevention of post-extraction complications. New studies published between 2015 and
2025 were selected, including clinical trials, systematic reviews, and experimental
studies that demonstrated the efficacy of PRF in tissue regeneration, pain reduction,
edema reduction, and dry socket reduction, as well as significant improvement in
patients' functional recovery. The methodology adopted allowed for a consolidated
analysis of the available scientific evidence, highlighting the importance of
standardized protocols and the influence of individual variability on clinical response.
The results demonstrate the privacy, safety, and low cost of PRF, recommending its
routine use in minor oral surgery procedures. It is concluded that PRF represents a
significant advance in regenerative dentistry, requiring future studies aimed atimproving its applications and ensuring greater clinical predictability.
