MEDICAMENTOS DE LIBERAÇÃO MODIFICADA POR VIA ORAL E SUAS APLICAÇÕES NA CLÍNICA

Abstract

Modified drug release systems represent one of the classes of drugs developed to improve the pharmacokinetic profile of drugs, mainly in relation to their bioavailability being characterized by the processes of coatings, prolonged and delayed release and the degree of absorption of drugs. This work aimed to compare the modified-release drugs and their clinical applications, characterizing the possible types of coatings and analyzing the degree of absorption of the drugs, discussing the advantages of formulations compared to pharmaceutical forms of prolonged or delayed release. According to the bibliographic survey it was possible to observe that these drugs reduce the frequency of administration, decrease side effects, promoting advantages in relation to patient compliance to treatment. The modified-release drugs are developed to allow a better use of the drug by the body, being them effective, safe, with curative purposes, for relief, promoting a treatment of great foundation and prevention. In view of the arguments presented, it is possible to clarify the functionality and the possible classes of drugs by oral route of modified release, becoming a safe means of easy administration and ensuring total safety to the patient in relation to their pharmacological treatment.