SOUZA, Ana Carolinny Martins de; COSTA, Mirian Guerra de Oliveira; NICARETTA, João Eduardo
Abstract:
This study analyzes obesity in dogs, a condition that involves multiple factors, is
highly prevalent, and harms their health. It is also linked to diseases such as diabetes
mellitus, osteoarthritis, and cardiovascular disease. The objective of this study was to
evaluate the efficacy of the alternative pharmacological therapies dirlotapide and
mitratapide in controlling body weight in obese dogs, comparing their effects to
conventional treatment based on diet and exercise. To this end, a systematic
literature review was conducted using scientific articles from national and
international databases. The findings demonstrate that both medications provide
significant weight loss by interfering with lipid absorption and stimulating satiety, with
improved results when combined with balanced diets and physical activity programs.
It was also found that these medications can help manage obesity comorbidities,
although they can cause side effects such as vomiting, diarrhea, and enzyme
alterations, in addition to requiring ongoing veterinary care. It can be concluded that
dirlotapide and mitratapide represent a viable and effective alternative to the
treatment of canine obesity, as long as they are used in an integrated manner with
conventional treatment modalities under the guidance of a veterinarian, ensuring
benefits in both health and quality of life of the animals.
