O USO DE TERAPÊUTICAS ALTERNATIVAS COMO DIRLOTAPIDE E MITRATAPIDE NA MODULAÇÃO DO PESO CORPORAL DE CÃES OBESOS

Abstract

This study analyzes obesity in dogs, a condition that involves multiple factors, is highly prevalent, and harms their health. It is also linked to diseases such as diabetes mellitus, osteoarthritis, and cardiovascular disease. The objective of this study was to evaluate the efficacy of the alternative pharmacological therapies dirlotapide and mitratapide in controlling body weight in obese dogs, comparing their effects to conventional treatment based on diet and exercise. To this end, a systematic literature review was conducted using scientific articles from national and international databases. The findings demonstrate that both medications provide significant weight loss by interfering with lipid absorption and stimulating satiety, with improved results when combined with balanced diets and physical activity programs. It was also found that these medications can help manage obesity comorbidities, although they can cause side effects such as vomiting, diarrhea, and enzyme alterations, in addition to requiring ongoing veterinary care. It can be concluded that dirlotapide and mitratapide represent a viable and effective alternative to the treatment of canine obesity, as long as they are used in an integrated manner with conventional treatment modalities under the guidance of a veterinarian, ensuring benefits in both health and quality of life of the animals.